Organo-Metalloid Compounds
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- (115)
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Filtered Search Results
Medchemexpress LLC Pomalidomide-PEG3-C2-NH2 TFA | 2414913-97-4 | 99.0% | 2 G
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Pomalidomide-PEG3-C2-NH2 TFA is a synthetic E3 ligase ligand-linker conjugate, featuring a Pomalidomide-based cereblon ligand and a 3-unit PEG linker. This compound is designed for the synthesis of PROTACs and is intended for research use only.
- Synthetic E3 ligase ligand-linker conjugate
- Features a Pomalidomide-based cereblon ligand and 3-unit PEG linker
- Utilized for the synthesis of PROTACs
- High purity: 99.0%
- Molecular weight: 562.49
- Chemical formula: C23H29F3N4O9
- Appears as a light yellow to yellow solid-liquid mixture
- Soluble in DMSO, ethanol, and water
- Offers multiple dissolution protocols for in vivo studies
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Medchemexpress LLC Acetic acid, 2-(2,4-dichlorophenoxy)-, isooctyl ester | 25168-26-7 | 97.2% | 250 MG
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2,4-D isooctyl ester is a selective herbicide belonging to the chlorophenoxy compound class. It is characterized by a higher boiling point, low volatility, and low drift, making it effective for controlling broadleaf weeds in various settings such as crops, lawns, and forests. This product is for research use only.
- Selective herbicide
- Chlorophenoxy compound
- Higher boiling point, low volatility, and low drift
- Controls broadleaf weeds
- Suitable for use in crops, lawns, and forests
- Purity: 97.17%
- Molecular formula: C16H22Cl2O3
- Molecular weight: 333.25
- Appearance: Colorless to light yellow liquid
- Soluble in DMSO (≥ 175 mg/mL)
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Medchemexpress LLC 5,8,11-trioxa-2-azatetradecanedioic acid, 1-(9H-fluoren-9-ylmethyl) ester | 867062-95-1 | 99.8% | 443.49 g/mol | C24H29NO7 | 1 G
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Fmoc-NH-PEG3-CH2CH2COOH is an Fmoc-protected PEG3 linker bearing a terminal carboxylic acid, used in research applications as a cleavable linker for antibody-drug conjugates and as a PEG-based linker for PROTAC synthesis.
- Fmoc-protected amine functionality for standard peptide chemistry
- Terminal carboxylic acid for conjugation
- High reported purity (≈99.8%)
- Molecular weight 443.49 g/mol
- Chemical formula C24H29NO7
- Available in small-scale quantities, including 1 G
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Medchemexpress LLC NH-bis(PEG3-azide) | 1258939-39-7 | 98.0% | C16H33N7O6 | 50 MG
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NH-bis(PEG3-azide) is a PEG-based PROTAC linker used in PROTAC synthesis. It is a click chemistry reagent containing an Azide group, which can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with Alkyne groups or strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Can be used in the synthesis of PROTACs.
- Contains an azide group, facilitating click chemistry reactions.
- Undergoes copper-catalyzed azide-alkyne cycloaddition (CuAAc) with alkyne groups.
- Undergoes strain-promoted alkyne-azide cycloaddition (SPAAC) with DBCO or BCN groups.
- Exploits the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
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Medchemexpress LLC THP-PEG3-OH | 60221-37-6 | 98.7% | 10 G
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THP-PEG3-OH is a PEG-based PROTAC linker designed for use in the synthesis of PROTACs. PROTACs are compounds that exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins. They consist of two different ligands connected by a linker, with one ligand binding to an E3 ubiquitin ligase and the other to the target protein.
- PEG-based PROTAC linker
- Molecular formula: C11H22O5
- Molecular weight: 234.29
- Appearance: Liquid
- Color: Colorless to light yellow
- For research use only
- Target: PROTAC linkers
- Pathway: PROTAC
- Storage (pure form): -20°C for 3 years; 4°C for 2 years
- Storage (in solvent): -80°C for 6 months; -20°C for 1 month
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Medchemexpress LLC HO-PEG3- CH2 6-Cl
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HO-PEG3-(CH2)6-Cl is a PROTAC linker that can be used to synthesize HaloPROTAC-E (HY-145752)[1]
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Medchemexpress LLC Tos-PEG5-Boc | 581065-94-3 | ≥97.0% | 5 G
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Tos-PEG5-Boc is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting an E3 ubiquitin ligase ligand and a target protein ligand via a linker. It has a molecular weight of 476.58 and the formula C22H36O9S, appearing as a viscous liquid that is colorless to light yellow.
- PEG-based PROTAC linker
- Used for the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- Viscous liquid, colorless to light yellow appearance
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Medchemexpress LLC Mal-amido-PEG3-acid | 2055353-75-6 | 372.37 | 50 MG
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Mal-amido-PEG3-acid is a PEG-based PROTAC linker used in the synthesis of PROTACs. PROTACs are designed to exploit the intracellular ubiquitin-proteasome system, selectively degrading target proteins by connecting an E3 ubiquitin ligase ligand to a target protein ligand via a linker.
- PEG-based linker
- Used in PROTAC synthesis
- Exploits ubiquitin-proteasome system
- Facilitates selective degradation of target proteins
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC PEG3-C4-OBn | 2381196-79-6 | 99.3% | 100 MG
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PEG3-C4-OBn is a polyethylene glycol (PEG)-based PROTAC linker. It can be used in the synthesis of the PROTAC SGK3 degrader-1, which is a potent SKG3 degrader.
- Polyethylene glycol (PEG)-based PROTAC linker
- Used in the synthesis of PROTAC SGK3 degrader-1
- High solubility in DMSO (≥ 100 mg/mL)
- Long-term stability in pure form at -20°C (3 years) and 4°C (2 years)
- Extended stability in solvent at -80°C (6 months) and -20°C (1 month)
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Medchemexpress LLC I-PEG5-OH 100mg
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I-PEG5-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]
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Medchemexpress LLC Tos-PEG5-Boc | 581065-94-3 | ≥97.0% | 250 MG
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Tos-PEG5-Boc is a PEG-based PROTAC linker designed for the synthesis of PROTACs. These molecules exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins by connecting a ligand for an E3 ubiquitin ligase and a ligand for the target protein. It has a molecular weight of 476.58 and a chemical formula of C22H36O9S. Its appearance is a viscous liquid, colorless to light yellow.
- PEG-based PROTAC linker
- Used in the synthesis of PROTACs
- Exploits the ubiquitin-proteasome system
- Selectively degrades target proteins
- Viscous liquid, colorless to light yellow appearance
- For research use only
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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Medchemexpress LLC (S,R,S)-AHPC-C2-PEG3-BCN | 2876198-36-4 | 99.2% | 810.01 g·mol⁻¹ | C42H59N5O9S | 10 MG
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(S,R,S)-AHPC-C2-PEG3-BCN (Compound 16b) is a VHL E3 ligase ligand-linker conjugate used as a building block in the synthesis of PROTACs and other conjugates. It features a PEG3 spacer and a bicyclononyne (BCN) functional group to facilitate bioorthogonal conjugation and assembly of bifunctional molecules for targeted protein degradation research.
- VHL E3 ligase ligand for targeted protein degradation applications.
- PEG3 linker provides a flexible spacer for molecular conjugation.
- BCN functional group enables strain-promoted bioorthogonal click conjugation.
- Reported high purity suitable for synthetic chemistry use.
- Intended as a small-molecule building block for PROTAC assembly and conjugation workflows.
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Medchemexpress LLC S R S-Ahpc-Peg3-Nh2 25Mg | HY-103602-25MG
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S R S-Ahpc-Peg3-Nh2 25Mg
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Medchemexpress LLC Azido-PEG5-acid | 1425973-16-5 | MFCD23726612 | >98.0% | 335.35 g/mol | C13H25N3O7 | 100 MG
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Azido-PEG5-acid is an azide-terminated polyethylene glycol (PEG5) linker designed for click chemistry and bioconjugation. It features a terminal carboxylic acid and an azide functional group that enable copper-catalyzed azide-alkyne cycloaddition (CuAAC) and strain-promoted azide-alkyne cycloaddition (SPAAC), making it useful for PROTAC construction, ADC linker assembly, and general spacer chemistry.
- Azide-terminated PEG5 spacer for bioconjugation
- Compatible with CuAAC and SPAAC click reactions
- High purity for reliable coupling
- Colorless to light yellow liquid, easy to handle
- Stable under recommended storage conditions
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![Medchemexpress LLC Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-methylbenzenesulfonate) | 77544-68-4 | 97.0% | 304.36 | 25 G](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000403297-logo.png-250.jpg){kind=logo}
Medchemexpress LLC Ethanol, 2-[2-(2-hydroxyethoxy)ethoxy]-, 1-(4-methylbenzenesulfonate) | 77544-68-4 | 97.0% | 304.36 | 25 G
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Small and/or specialty supplier based on Federal laws and SBA requirements.
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Tos-PEG3 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. It can also be used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
- Peg-based protac linker in the synthesis of protacs.
- Used for the synthesis of 3'-aminooxy oligonucleotides solid supports.
Non-distribution item offered as a customer accommodation; additional freight charges may apply.
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